De modo a minimizar o risco por hematomas, é importante escolher um profissional experiente e qualificado de modo a fazer este procedimento.
A one inch needle may be needed in the neck region for patients with thick neck muscles. With the exception of the procerus muscle, which should be injected at one site (midline), all muscles should be injected bilaterally with half the number of injection sites administered to the left, and half to the right side of the head and neck. The recommended re-treatment schedule is every 12 weeks.
In 1997, the original formulation was changed to reduce the protein load per dose, and since then treatment failure rates have dropped; however, experts estimate that 0.3 to 6% of people are still at risk of antibody development. The risk is greatest when dosages of more than 200 units per session are used, and reinjection occurs within one month. Experts are unsure if neutralizing antibodies resolve over time or if injections of botulinum toxin type B products are useful in patients with neutralizing antibodies to type A.
Getting "too much" Botox often means exceeding the amount needed for this subtle result, leading to undesirable cosmetic outcomes or potentially increasing side effect risks. It is important to be treated by a qualified, experienced medical professional (like a board-certified dermatologist, plastic surgeon, or properly trained nurse practitioner/physician assistant under supervision) who understands anatomy and appropriate dosing.
In general, the initial effect of the injections is seen within three days and reaches a peak at one to two weeks post-treatment. Each treatment lasts approximately three months, following which the procedure can be repeated. At repeat treatment sessions, the dose may be increased up to two-fold if the response from the initial treatment is considered insufficient, usually defined as an effect that does not last longer than two months.
Botox for medical conditions should only be injected by a trained healthcare provider who can ensure:
Botox should only ever be injected by a licensed provider. Do NOT attempt to inject this at home yourself as serious and potentially life-threatening side effects may occur. Licensed providers use a thin needle to inject Botox into the targeted muscle or gland.
The duration of post-injection catheterization for those who developed urinary retention is also shown.
In patients 12 years of age or older: Consider an intravesical instillation of diluted local anesthetic with or without sedation, or general anesthesia prior to injection, per local sitio practice.
These are biological products that have already been approved by the FDA, against liftera which biosimilar products are compared. There are 2 for onabotulinumtoxinA.
In adult spasticity patients with reduced lung function, upper respiratory tract infections were also reported more frequently as adverse reactions in patients treated with BOTOX than in patients treated with placebo [see Warnings and Precautions (5.10)].
Swallowing problems may last for several months. People who cannot swallow well may need a feeding tube to receive food and water.
Botox (onabotulinumtoxinA) for migraines is injected into 7 specific muscle areas around your head and neck to help prevent migraine headaches or migraine attacks before they start.
The following adverse reactions to BOTOX (onabotulinumtoxinA) for injection are discussed in greater detail in other sections of the labeling: